Version 5.4
Mus musculus Protein: Slc29a3
Summary
InnateDB Protein IDBP-401265.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc29a3
Protein Name solute carrier family 29 (nucleoside transporters), member 3
Synonyms 4933435C21Rik; AW987637; Ent3;
Species Mus musculus
Ensembl Protein ENSMUSP00000112685
InnateDB Gene IDBG-154980 (Slc29a3)
Protein Structure
UniProt Annotation
Function Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine (By similarity). {ECO:0000250}.
Subcellular Localization Membrane; Multi-pass membrane protein. Late endosome membrane. Lysosome membrane. Note=Intracellular localization shows a partial overlap with late endosomes/lysosomes. Not detected at the cell surface (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005337 nucleoside transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0015858 nucleoside transport
GO:1901642 nucleoside transmembrane transport
Cellular Component
GO:0005765 lysosomal membrane
GO:0016021 integral component of membrane
GO:0031902 late endosome membrane
Protein Structure and Domains
PDB ID MGI:1918529
InterPro IPR002259 Equilibrative nucleoside transporter
PFAM PF01733
PRINTS PR01130
PIRSF PIRSF016379
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99P65
PhosphoSite PhosphoSite-Q99P65
TrEMBL
UniProt Splice Variant
Entrez Gene 71279
UniGene Mm.284462
RefSeq NP_076085
MGI ID
MGI Symbol Slc29a3
OMIM
CCDS CCDS48571
HPRD
IMGT
EMBL AF326986 AK034133 BC137864 CH466553
GenPept AAI37865 AAK00957 BAC28600 EDL32166

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca