InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ttpa

Summary

InnateDB Protein

IDBP-401339.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ttpa

Protein Name

tocopherol (alpha) transfer protein

Synonyms

alpha-TTP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113026

InnateDB Gene

IDBG-131247 (Ttpa)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0008431	vitamin E binding

Biological Process

GO:0001890	placenta development
GO:0001892	embryonic placenta development
GO:0006810	transport
GO:0007584	response to nutrient
GO:0009268	response to pH
GO:0042360	vitamin E metabolic process
GO:0051452	intracellular pH reduction
GO:0060548	negative regulation of cell death

Cellular Component

GO:0005737	cytoplasm
GO:0005770	late endosome
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

MGI:1354168

InterPro

IPR001071 Cellular retinaldehyde binding/alpha-tocopherol transport
IPR001251 CRAL-TRIO domain
IPR011074 CRAL/TRIO, N-terminal domain

PFAM

PF00650
PF13716
PF03765

PRINTS

PR00180

PIRSF

SMART

SM00516
SM01100

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A8Y5P0

UniProt Splice Variant

Entrez Gene

50500

UniGene

Mm.416566

RefSeq

MGI ID

MGI Symbol

Ttpa

OMIM

CCDS

HPRD

IMGT

EMBL

AL732527

GenPept