Version 5.4
Mus musculus Protein: Pfn2
Summary
InnateDB Protein IDBP-401426.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pfn2
Protein Name profilin 2
Synonyms Pfn;
Species Mus musculus
Ensembl Protein ENSMUSP00000112443
InnateDB Gene IDBG-146219 (Pfn2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0030036 actin cytoskeleton organization
GO:0030837 negative regulation of actin filament polymerization
GO:0030838 positive regulation of actin filament polymerization
GO:2000300 regulation of synaptic vesicle exocytosis
Cellular Component
GO:0043195 terminal bouton
Protein Structure and Domains
PDB ID MGI:97550
InterPro IPR005454 Profilin, chordates
IPR005455 Profilin
PFAM PF00235
PRINTS PR01639
PR00392
PR01640
PIRSF
SMART SM00392
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3YWS3
UniProt Splice Variant
Entrez Gene 18645
UniGene Mm.271744
RefSeq
MGI ID
MGI Symbol Pfn2
OMIM
CCDS
HPRD
IMGT
EMBL AC165888
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca