InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Trim24

Summary

InnateDB Protein

IDBP-401482.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Trim24

Protein Name

tripartite motif-containing 24

Synonyms

A130082H20Rik; AI447469; D430004I05Rik; TIF1; TIF1-alpha; Tif1a; TIF1alpha;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000114001

InnateDB Gene

IDBG-136387 (Trim24)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.

Experimentally validated
Total	25 [view]
Protein-Protein	25 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	39 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0004672	protein kinase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016922	ligand-dependent nuclear receptor binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006468	protein phosphorylation
GO:0008285	negative regulation of cell proliferation
GO:0010628	positive regulation of gene expression
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0046777	protein autophosphorylation
GO:0055074	calcium ion homeostasis
GO:0070562	regulation of vitamin D receptor signaling pathway
GO:1901796	regulation of signal transduction by p53 class mediator

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005719	nuclear euchromatin
GO:0005726	perichromatin fibrils
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:109275

InterPro

IPR000315 Zinc finger, B-box
IPR001487 Bromodomain
IPR001965 Zinc finger, PHD-type
IPR003649 B-box, C-terminal
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger

PFAM

PF00643
PF00439
PF00628

PRINTS

PR00503

PIRSF

SMART

SM00336
SM00297
SM00249
SM00502

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt