Version 5.4
Mus musculus Protein: Unc50
Summary
InnateDB Protein IDBP-401529.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Unc50
Protein Name unc-50 homolog (C. elegans)
Synonyms 1110002A21Rik; GMH1; UNCL; URP;
Species Mus musculus
Ensembl Protein ENSMUSP00000113135
InnateDB Gene IDBG-145986 (Unc50)
Protein Structure
UniProt Annotation
Function May be involved in cell surface expression of neuronal nicotinic receptors. Binds RNA (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus inner membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in periodontal ligament and bone marrow, but not in gingival fibroblasts. {ECO:0000269PubMed:11302735}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0015031 protein transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005637 nuclear inner membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1914637
InterPro IPR007881 UNC-50
PFAM PF05216
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CQ61
PhosphoSite PhosphoSite-
TrEMBL D3YXX4
UniProt Splice Variant
Entrez Gene 67387
UniGene Mm.27404
RefSeq XP_006496282
MGI ID
MGI Symbol Unc50
OMIM
CCDS CCDS14892
HPRD
IMGT
EMBL AC084390 AK003273 AK004433 AK132757 AK135885 AY017214 BC019484
GenPept AAH19484 AAK08986 BAB22683 BAB23302 BAE21338 BAE22715

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca