Version 5.4
Mus musculus Protein: Mtfr1
Summary
InnateDB Protein IDBP-401676.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtfr1
Protein Name mitochondrial fission regulator 1
Synonyms 1300002C08Rik; 1700080D04Rik; 2810026O10Rik; 4930579E05Rik; Chppr; Fam54a2;
Species Mus musculus
Ensembl Protein ENSMUSP00000112824
InnateDB Gene IDBG-132424 (Mtfr1)
Protein Structure
UniProt Annotation
Function May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission. {ECO:0000269PubMed:20568109}.
Subcellular Localization Mitochondrion {ECO:0000250}. Note=May be associated with the inner and the outer mitochondrial membrane. {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitously expressed with higher expression in testis. {ECO:0000269PubMed:17709566}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000266 mitochondrial fission
GO:0007005 mitochondrion organization
GO:0009060 aerobic respiration
Cellular Component
GO:0005739 mitochondrion
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:1914722
InterPro IPR007972 Mitochondrial fission regulator 1
PFAM PF05308
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99MB2
PhosphoSite PhosphoSite-Q99MB2
TrEMBL Q3TTQ5
UniProt Splice Variant
Entrez Gene 67472
UniGene Mm.489766
RefSeq NP_001240320
MGI ID
MGI Symbol Mtfr1
OMIM
CCDS CCDS17256
HPRD
IMGT
EMBL AC127283 AF354708 AK004846 AK006952 AK075822 AK075992 AK161251 BC019971 CH466530 DQ369744
GenPept AAH19971 AAK26434 ABC96324 BAB23612 BAB24802 BAC35988 BAC36103 BAE36270 EDL34873 EDL34875

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca