Version 5.4
Mus musculus Protein: Fuca2
Summary
InnateDB Protein IDBP-401677.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fuca2
Protein Name fucosidase, alpha-L- 2, plasma
Synonyms 0610025O11Rik; 5530401P20Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000113499
InnateDB Gene IDBG-134255 (Fuca2)
Protein Structure
UniProt Annotation
Function Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004560 alpha-L-fucosidase activity
GO:0042806 fucose binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006004 fucose metabolic process
GO:0009617 response to bacterium
GO:0016139 glycoside catabolic process
GO:2000535 regulation of entry of bacterium into host cell
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1914098
InterPro IPR000933 Glycoside hydrolase, family 29
IPR016286 Alpha-L-fucosidase, metazoa-type
IPR017853 Glycoside hydrolase, superfamily
PFAM PF01120
PRINTS PR00741
PIRSF PIRSF001092
SMART SM00812
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99KR8
PhosphoSite PhosphoSite-
TrEMBL Q505Q3
UniProt Splice Variant
Entrez Gene 66848
UniGene Mm.412446
RefSeq NP_080075
MGI ID
MGI Symbol Fuca2
OMIM
CCDS CCDS23701
HPRD
IMGT
EMBL AC153979 AK002675 AK008653 AK030320 AK035607 AK146295 AK151204 AK159288 BC004039 BC018181 BC094449 CH466562
GenPept AAH04039 AAH18181 AAH94449 BAB22277 BAB25809 BAC26899 BAC29123 BAE27052 BAE30201 BAE34964 EDL03501 EDL03502

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca