InnateDB Protein
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IDBP-40647.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CCL11
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Protein Name
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chemokine (C-C motif) ligand 11
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Synonyms
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SCYA11;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000302234
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InnateDB Gene
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IDBG-40645 (CCL11)
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Protein Structure
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|
Function |
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
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Subcellular Localization |
Secreted.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
21
[view]
|
Protein-Protein |
15
[view]
|
Protein-DNA |
6
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001811
Chemokine interleukin-8-like domain
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PFAM |
PF00048
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PRINTS |
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PIRSF |
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SMART |
SM00199
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TIGRFAMs |
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Modification |
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SwissProt |
P51671
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PhosphoSite |
PhosphoSite-P51671
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TrEMBL |
Q6I9T4
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UniProt Splice Variant |
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Entrez Gene |
6356
|
UniGene |
Hs.604705
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RefSeq |
NP_002977
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HUGO |
HGNC:10610
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OMIM |
601156
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CCDS |
CCDS11279
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HPRD |
03098
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IMGT |
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EMBL |
BC017850
CH471147
CR457421
D49372
EF064768
U34780
U46572
U46573
Z69291
Z75668
Z75669
Z92709
|
GenPept |
AAA98957
AAC50369
AAC51297
AAH17850
ABK41951
BAA08370
CAA93258
CAA99997
CAA99998
CAB07027
CAG33702
EAW80209
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