Version 5.4
Homo sapiens Protein: CPA2
Summary
InnateDB Protein IDBP-41199.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPA2
Protein Name carboxypeptidase A2 (pancreatic)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000222481
InnateDB Gene IDBG-41197 (CPA2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0004181 metallocarboxypeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0007039 vacuolar protein catabolic process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000834 Peptidase M14, carboxypeptidase A
IPR003146 Proteinase inhibitor, carboxypeptidase propeptide
IPR009020 Proteinase inhibitor, propeptide
PFAM PF00246
PF02244
PRINTS PR00765
PIRSF
SMART SM00631
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48052
PhosphoSite PhosphoSite-P48052
TrEMBL
UniProt Splice Variant
Entrez Gene 1358
UniGene Hs.490038
RefSeq NP_001860
HUGO HGNC:2297
OMIM 600688
CCDS CCDS5817
HPRD 02821
IMGT
EMBL AC024085 BC007009 BC014571 BC015140 BT007403 CH236950 U19977
GenPept AAA74425 AAH07009 AAH14571 AAH15140 AAP36067 EAL24092

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca