Version 5.4
Homo sapiens Protein: HP
Summary
InnateDB Protein IDBP-41492.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HP
Protein Name haptoglobin
Synonyms BP; HP2ALPHA2; HPA1S;
Species Homo sapiens
Ensembl Protein ENSP00000350406
InnateDB Gene IDBG-547150 (HP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0030492 hemoglobin binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000436 Sushi/SCR/CCP
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00084
PF00089
PRINTS PR00722
PIRSF
SMART SM00032
SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6PEJ8
UniProt Splice Variant
Entrez Gene 3250
UniGene Hs.513711
RefSeq
HUGO HGNC:5141
OMIM 140210
CCDS
HPRD 00772
IMGT
EMBL AC009087 BC017862 BC058031
GenPept AAH17862 AAH58031

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca