InnateDB Protein
|
IDBP-4152.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
MTFP1
|
Protein Name
|
mitochondrial fission process 1
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000266263
|
InnateDB Gene
|
IDBG-402113 (MTFP1)
|
Protein Structure
|
|
Function |
Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function induces the release of cytochrome c, which activates the caspase cascade and leads to apoptosis. {ECO:0000269PubMed:15155745, ECO:0000269PubMed:15985469}.
|
Subcellular Localization |
Mitochondrion inner membrane {ECO:0000305PubMed:15155745, ECO:0000305PubMed:15985469}; Multi- pass membrane protein {ECO:0000305PubMed:15155745, ECO:0000305PubMed:15985469}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR019560
Mitochondrial 18kDa protein
|
PFAM |
PF10558
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9UDX5
|
PhosphoSite |
PhosphoSite-Q9UDX5
|
TrEMBL |
A0A024R1E4
|
UniProt Splice Variant |
|
Entrez Gene |
51537
|
UniGene |
|
RefSeq |
NP_057582
|
HUGO |
HGNC:26945
|
OMIM |
610235
|
CCDS |
CCDS33635
|
HPRD |
17612
|
IMGT |
|
EMBL |
AC004832
AF060924
AF151076
BC001608
BC009300
BC014446
BC030989
BC038831
BC046132
CH471095
CR456345
|
GenPept |
AAF19257
AAF36162
AAG43136
AAH01608
AAH09300
AAH14446
AAH30989
AAH38831
AAH46132
CAG30231
EAW59889
EAW59891
|
|
|