Version 5.4
Homo sapiens Protein: EXOC4
Summary
InnateDB Protein IDBP-41990.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXOC4
Protein Name exocyst complex component 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000253861
InnateDB Gene IDBG-41988 (EXOC4)
Protein Structure
UniProt Annotation
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 48 [view]
Protein-Protein 47 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030165 PDZ domain binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0006904 vesicle docking involved in exocytosis
GO:0015031 protein transport
GO:0044267 cellular protein metabolic process
GO:0061024 membrane organization
Cellular Component
GO:0000145 exocyst
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0032584 growth cone membrane
GO:0035748 myelin sheath abaxonal region
Protein Structure and Domains
PDB ID
InterPro IPR007191 Sec8 exocyst complex component specific domain
PFAM PF04048
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96A65
PhosphoSite PhosphoSite-Q96A65
TrEMBL B7Z4J9
UniProt Splice Variant
Entrez Gene 60412
UniGene Hs.691378
RefSeq NP_068579
HUGO HGNC:30389
OMIM 608185
CCDS CCDS5829
HPRD 12185
IMGT
EMBL AB051486 AC007790 AC009178 AC009180 AC009358 AC024086 AC083872 AC083875 AC093147 AF132734 AF380839 AK022751 AK027688 AK295404 AK297458 AL831989 AL834475 CH236950 CH471070
GenPept AAF66445 AAK57456 BAB14225 BAB21790 BAB55298 BAH12057 BAH12585 CAD39134 CAD89977 EAL24073 EAW83804

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca