Version 5.4
Homo sapiens Protein: PDCD2L
Summary
InnateDB Protein IDBP-42973.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDCD2L
Protein Name programmed cell death 2-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000246535
InnateDB Gene IDBG-42971 (PDCD2L)
Protein Structure
UniProt Annotation
Function Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase. {ECO:0000269PubMed:17393540}.
Subcellular Localization
Disease Associations
Tissue Specificity Higher expression in lung, colon, mammary gland, cervix, stomach and small intestine. {ECO:0000269PubMed:17393540}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007049 cell cycle
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR007320 Programmed cell death protein 2, C-terminal
PFAM PF04194
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BRP1
PhosphoSite PhosphoSite-Q9BRP1
TrEMBL U3KQL1
UniProt Splice Variant
Entrez Gene 84306
UniGene Hs.603182
RefSeq NP_115722
HUGO HGNC:28194
OMIM 615661
CCDS CCDS12438
HPRD 17480
IMGT
EMBL AC008747 AC092073 BC006146
GenPept AAH06146

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca