InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LSR

Summary

InnateDB Protein

IDBP-43668.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LSR

Protein Name

lipolysis stimulated lipoprotein receptor

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000262627

InnateDB Gene

IDBG-43660 (LSR)

Protein Structure

UniProt Annotation

Function

Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity). {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001889	liver development
GO:0009790	embryo development

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0034361	very-low-density lipoprotein particle
GO:0034362	low-density lipoprotein particle
GO:0042627	chylomicron
GO:0070062	extracellular vesicular exosome