Version 5.4
Homo sapiens Protein: MTCH2
Summary
InnateDB Protein IDBP-43763.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTCH2
Protein Name mitochondrial carrier 2
Synonyms MIMP; SLC25A50;
Species Homo sapiens
Ensembl Protein ENSP00000303222
InnateDB Gene IDBG-43761 (MTCH2)
Protein Structure
UniProt Annotation
Function The substrate transported is not yet known. Induces mitochondrial depolarization.
Subcellular Localization Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
GO:0070585 protein localization to mitochondrion
GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00153
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y6C9
PhosphoSite PhosphoSite-Q9Y6C9
TrEMBL F5H3Y2
UniProt Splice Variant
Entrez Gene 23788
UniGene Hs.641826
RefSeq NP_055157
HUGO HGNC:17587
OMIM 613221
CCDS CCDS7943
HPRD 14788
IMGT
EMBL AC104942 AF085361 AF176008 AK313032 AY380792 BC000875 CH471064
GenPept AAD40196 AAD52646 AAH00875 AAQ88168 BAG35865 EAW67892

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca