Version 5.4
Homo sapiens Protein: RASSF3
Summary
InnateDB Protein IDBP-45058.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RASSF3
Protein Name Ras association (RalGDS/AF-6) domain family member 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000336616
InnateDB Gene IDBG-45056 (RASSF3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000269PubMed:15569673}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:15569673}. Note=Localized to microtubules in vascular endothelial cells.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:11965544}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR000159 Ras-association
IPR011524 SARAH domain
IPR029071 Ubiquitin-related domain
PFAM PF00788
PRINTS
PIRSF
SMART SM00314
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86WH2
PhosphoSite PhosphoSite-Q86WH2
TrEMBL Q496A9
UniProt Splice Variant
Entrez Gene 283349
UniGene Hs.643605
RefSeq
HUGO HGNC:14271
OMIM 607019
CCDS CCDS8969
HPRD 08448
IMGT
EMBL AY217662 AY217663 BC100949 BC100950 BC100951 BC100952
GenPept AAI00950 AAI00951 AAI00952 AAI00953 AAO61687 AAO61688

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca