InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CNTN3

Summary

InnateDB Protein

IDBP-45122.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CNTN3

Protein Name

contactin 3 (plasmacytoma associated)

Synonyms

BIG-1; PANG; PCS;

Species

Homo sapiens

Ensembl Protein

ENSP00000263665

InnateDB Gene

IDBG-45120 (CNTN3)

Protein Structure

UniProt Annotation

Function

Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity (By similarity). {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.

Disease Associations

Tissue Specificity

In brain, it is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. {ECO:0000269PubMed:11013081}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007399	nervous system development

Cellular Component

GO:0005886	plasma membrane
GO:0031225	anchored component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF07686
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9P232