Version 5.4
Homo sapiens Protein: PIP
Summary
InnateDB Protein IDBP-45592.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIP
Protein Name prolactin-induced protein
Synonyms GCDFP-15; GCDFP15; GPIP4;
Species Homo sapiens
Ensembl Protein ENSP00000291009
InnateDB Gene IDBG-45590 (PIP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Expressed in pathological conditions of the mammary gland and in several exocrine tissues, such as the lacrimal, salivary, and sweat glands.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001948 glycoprotein binding
GO:0003779 actin binding
GO:0004190 aspartic-type endopeptidase activity
GO:0005515 protein binding
GO:0019864 IgG binding
GO:0046983 protein dimerization activity
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0001895 retina homeostasis
GO:0002682 regulation of immune system process
GO:0006508 proteolysis
GO:0010628 positive regulation of gene expression
GO:0070233 negative regulation of T cell apoptotic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR007990 Seminal vesicle autoantigen
PFAM PF05326
PRINTS
PIRSF PIRSF002572
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P12273
PhosphoSite PhosphoSite-P12273
TrEMBL
UniProt Splice Variant
Entrez Gene 5304
UniGene Hs.99949
RefSeq NP_002643
HUGO HGNC:8993
OMIM 176720
CCDS CCDS34768
HPRD 07179
IMGT
EMBL AB267097 AB267098 AB267099 AB267100 AB267101 AB267102 AB267103 AB267104 AB267105 AB267106 AB267107 AB267108 AB267109 AB267110 AB267111 AB267112 AB267113 AB267114 AB267115 AB267116 AB267117 AB267118 AB267119 AB267120 AB267121 AB267122 AB267123 AB267124 AB267125 AB267126 AB267127 AB267128 AB267129 AB267130 AB267131 AB267132 AB267133 AB267134 AB267135 AB267136 AB267137 AB267138 AB267139 AB267140 AB267141 AB267142 AB267143 AB267144 AB267145 AB267146 AB267147 AB267148 AB267149 AB267150 AB267151 AB267152 AB267153 AB267154 AB267155 AB267156 AB267157 AB267158 AB267159 AB267160 AB267161 AB267162 AB267163 AB267164 AB267165 AB267166 AB267167 AB267168 AB267169 AB267170 AB267171 AB267172 AB267173 AB267174 AB267175 AB267176 AB267177 AB267178 AB267179 AB267180 AB267181 AB267182 AB267183 AB267184 AB267185 AB267186 AB267187 AB267188 AB267189 AB267190 AB267191 AB267192 AB267193 AB267194 AB267195 AB267196 AB267197 AB267198 AB267199 AB267200 AB267201 AB267202 AB267203 AB267204 AB267205 AB267206 AB267207 AB267208 AB267209 AB267210 AB267211 AB267212 AB267213 AB267214 AB267215 AB267216 AK312227 BC010950 BC010951 CH236959 CH471198 J03460 X51501 X51502 X51504 Y10179
GenPept AAA60091 AAH10950 AAH10951 BAF35627 BAF35628 BAF35629 BAF35630 BAF35631 BAF35632 BAF35633 BAF35634 BAF35635 BAF35636 BAF35637 BAF35638 BAF35639 BAF35640 BAF35641 BAF35642 BAF35643 BAF35644 BAF35645 BAF35646 BAF35647 BAF35648 BAF35649 BAF35650 BAF35651 BAF35652 BAF35653 BAF35654 BAF35655 BAF35656 BAF35657 BAF35658 BAF35659 BAF35660 BAF35661 BAF35662 BAF35663 BAF35664 BAF35665 BAF35666 BAF35667 BAF35668 BAF35669 BAF35670 BAF35671 BAF35672 BAF35673 BAF35674 BAF35675 BAF35676 BAF35677 BAF35678 BAF35679 BAF35680 BAF35681 BAF35682 BAF35683 BAF35684 BAF35685 BAF35686 BAF35687 BAF35688 BAF35689 BAF35690 BAF35691 BAF35692 BAF35693 BAF35694 BAF35695 BAF35696 BAF35697 BAF35698 BAF35699 BAF35700 BAF35701 BAF35702 BAF35703 BAF35704 BAF35705 BAF35706 BAF35707 BAF35708 BAF35709 BAF35710 BAF35711 BAF35712 BAF35713 BAF35714 BAF35715 BAF35716 BAF35717 BAF35718 BAF35719 BAF35720 BAF35721 BAF35722 BAF35723 BAF35724 BAF35725 BAF35726 BAF35727 BAF35728 BAF35729 BAF35730 BAF35731 BAF35732 BAF35733 BAF35734 BAF35735 BAF35736 BAF35737 BAF35738 BAF35739 BAF35740 BAF35741 BAF35742 BAF35743 BAF35744 BAF35745 BAF35746 BAG35160 CAA35870 CAA71252 EAL23781 EAW51887

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca