Version 5.4
Homo sapiens Protein: TNKS1BP1
Summary
InnateDB Protein IDBP-46363.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNKS1BP1
Protein Name tankyrase 1 binding protein 1, 182kDa
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000350990
InnateDB Gene IDBG-46361 (TNKS1BP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus. Cytoplasm, cytoskeleton. Chromosome. Note=Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.
Disease Associations
Tissue Specificity Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0019899 enzyme binding
GO:0030506 ankyrin binding
Biological Process
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0007004 telomere maintenance via telomerase
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005724 nuclear telomeric heterochromatin
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0030014 CCR4-NOT complex
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9C0C2
PhosphoSite PhosphoSite-Q9C0C2
TrEMBL E9PKK0
UniProt Splice Variant
Entrez Gene 85456
UniGene Hs.530730
RefSeq NP_203754
HUGO HGNC:19081
OMIM 607104
CCDS CCDS7951
HPRD 06164
IMGT
EMBL AB051528 AF441771 AK074113 AK124903 AP000781 BC023622 BC150333 CH471076
GenPept AAH23622 AAI50334 AAM15531 BAB21832 BAB84939 BAC85989 EAW73731 EAW73732 EAW73733

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca