InnateDB Protein
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IDBP-46751.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GSDMA
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Protein Name
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gasdermin A
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000301659
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InnateDB Gene
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IDBG-46749 (GSDMA)
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Protein Structure
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Function |
Induces apoptosis. {ECO:0000269PubMed:17471240}.
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Subcellular Localization |
Cytoplasm, perinuclear region {ECO:0000269PubMed:17471240}.
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Disease Associations |
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Tissue Specificity |
Expressed predominantly in the gastrointestinal tract and in the skin at a lower level. Also detected in mammary gland. Detected in mucus-secreting pit cells of the gastric epithelium. Not expressed in gastric cancer cells. {ECO:0000269PubMed:10967128, ECO:0000269PubMed:17471240}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007677
Gasdermin
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PFAM |
PF04598
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q96QA5
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PhosphoSite |
PhosphoSite-Q96QA5
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TrEMBL |
J3KRG2
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UniProt Splice Variant |
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Entrez Gene |
284110
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UniGene |
Hs.448873
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RefSeq |
NP_835465
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HUGO |
HGNC:13311
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OMIM |
611218
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CCDS |
CCDS45669
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HPRD |
17081
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IMGT |
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EMBL |
AB093591
AC090844
AF307953
AK096439
BC109197
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GenPept |
AAI09198
AAL14426
BAC04790
BAC75636
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