Version 5.4
Homo sapiens Protein: ZDHHC5
Summary
InnateDB Protein IDBP-47038.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZDHHC5
Protein Name zinc finger, DHHC-type containing 5
Synonyms DHHC5; ZNF375;
Species Homo sapiens
Ensembl Protein ENSP00000287169
InnateDB Gene IDBG-47036 (ZDHHC5)
Protein Structure
UniProt Annotation
Function Palmitoyl acyltransferase for the G-protein coupled receptor SSTR5. Also palmitoylates FLOT2 (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016409 palmitoyltransferase activity
GO:0019706 protein-cysteine S-palmitoyltransferase activity
Biological Process
GO:0007275 multicellular organismal development
GO:0018345 protein palmitoylation
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030425 dendrite
Protein Structure and Domains
PDB ID
InterPro IPR001594 Zinc finger, DHHC-type, palmitoyltransferase
IPR016201 Plexin-like fold
PFAM PF01529
PRINTS
PIRSF
SMART SM00423
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9C0B5
PhosphoSite PhosphoSite-Q9C0B5
TrEMBL E9PMA5
UniProt Splice Variant
Entrez Gene 25921
UniGene Hs.618777
RefSeq NP_056272
HUGO HGNC:18472
OMIM 614586
CCDS CCDS7965
HPRD 15720
IMGT
EMBL AB051535 AK023130 AK172807 AL117662 AP000662 AY894889 BC026967 CH471076
GenPept AAH26967 AAX73368 BAB14420 BAB21839 BAD18778 CAB56033 EAW73771 EAW73773

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca