InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HGFAC

Summary

InnateDB Protein

IDBP-475849.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HGFAC

Protein Name

HGF activator

Synonyms

HGFA;

Species

Homo sapiens

Ensembl Protein

ENSP00000421801

InnateDB Gene

IDBG-8130 (HGFAC)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding

Biological Process

GO:0006508

proteolysis

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0005791	rough endoplasmic reticulum

Protein Structure and Domains

PDB ID

InterPro

IPR000001 Kringle
IPR000083 Fibronectin, type I
IPR000562 Fibronectin, type II, collagen-binding
IPR000742 Epidermal growth factor-like domain
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR013806 Kringle-like fold
IPR014394 Coagulation factor XIIa/hepatocyte growth factor activator

PFAM

PF00051
PF00039
PF00040
PF00008
PF00089

PRINTS

PR00722

PIRSF

PIRSF001146

SMART

SM00130
SM00058
SM00059
SM00181
SM00020

TIGRFAMs

Post-translational Modifications

Modification

Cross-References