Version 5.4
Homo sapiens Protein: CDKN2AIP
Summary
InnateDB Protein IDBP-477110.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDKN2AIP
Protein Name CDKN2A interacting protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000427108
InnateDB Gene IDBG-45964 (CDKN2AIP)
Protein Structure
UniProt Annotation
Function Activates p53/TP53 by CDKN2A-dependent and CDKN2A- independent pathways. {ECO:0000269PubMed:15109303}.
Subcellular Localization Nucleus, nucleoplasm {ECO:0000269PubMed:12154087, ECO:0000269PubMed:12581788}.
Disease Associations
Tissue Specificity Ubiquitously expressed. {ECO:0000269PubMed:12581788}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0009967 positive regulation of signal transduction
GO:0030308 negative regulation of cell growth
GO:0031647 regulation of protein stability
Cellular Component
GO:0001652 granular component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR014720 Double-stranded RNA-binding domain
IPR021859 Protein of unknown function DUF3469
PFAM PF00035
PF11952
PRINTS
PIRSF
SMART SM00358
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NXV6
PhosphoSite PhosphoSite-Q9NXV6
TrEMBL B3KTW3
UniProt Splice Variant
Entrez Gene 55602
UniGene Hs.723492
RefSeq NP_060102
HUGO HGNC:24325
OMIM 615914
CCDS CCDS34110
HPRD 16683
IMGT
EMBL AF246705 AK000043 AK096180 BC022270 CH471056
GenPept AAF68967 AAH22270 BAA90902 BAG53225 EAX04691

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca