Version 5.4
Homo sapiens Protein: IL7
Summary
InnateDB Protein IDBP-477703.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL7
Protein Name interleukin 7
Synonyms IL-7;
Species Homo sapiens
Ensembl Protein ENSP00000430272
InnateDB Gene IDBG-26153 (IL7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 7 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005126 cytokine receptor binding
GO:0005139 interleukin-7 receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0006955 immune response
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000226 Interleukin-7/interleukin-9 family
IPR001181 Interleukin-7
PFAM PF01415
PRINTS PR00435
PIRSF PIRSF001942
SMART SM00127
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5FBY8
UniProt Splice Variant
Entrez Gene 3574
UniGene Hs.591873
RefSeq
HUGO HGNC:6023
OMIM 146660
CCDS
HPRD 00892
IMGT
EMBL AB102880 AB102885 AC083837 AC100854
GenPept BAD89409 BAD89414

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca