Version 5.4
Homo sapiens Protein: PI15
Summary
InnateDB Protein IDBP-478347.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PI15
Protein Name peptidase inhibitor 15
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000428567
InnateDB Gene IDBG-25928 (PI15)
Protein Structure
UniProt Annotation
Function Serine protease inhibitor which displays weak inhibitory activity against trypsin. {ECO:0000269PubMed:8882727}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Weakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland. {ECO:0000269PubMed:11287197, ECO:0000269PubMed:9473672}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0030414 peptidase inhibitor activity
Biological Process
GO:0008150 biological_process
GO:0010466 negative regulation of peptidase activity
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001283 Cysteine-rich secretory protein, allergen V5/Tpx-1-related
IPR014044 CAP domain
PFAM PF00188
PRINTS PR00837
PIRSF PIRSF038921
SMART SM00198
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43692
PhosphoSite PhosphoSite-O43692
TrEMBL
UniProt Splice Variant
Entrez Gene 51050
UniGene Hs.98558
RefSeq
HUGO HGNC:8946
OMIM 607076
CCDS CCDS6218
HPRD 06150
IMGT
EMBL BC074931 BC074932 BC126290 BC126292 CR749657 D45027
GenPept AAH74931 AAH74932 AAI26291 AAI26293 BAA25066 CAH18451

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca