Version 5.4
Homo sapiens Protein: LY6E
Summary
InnateDB Protein IDBP-478392.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LY6E
Protein Name lymphocyte antigen 6 complex, locus E
Synonyms RIG-E; RIGE; SCA-2; SCA2; TSA-1;
Species Homo sapiens
Ensembl Protein ENSP00000427915
InnateDB Gene IDBG-38103 (LY6E)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007166 cell surface receptor signaling pathway
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001526 CD59 antigen
IPR016054 Ly-6 antigen / uPA receptor -like
PFAM PF00021
PRINTS
PIRSF
SMART SM00134
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q16553
PhosphoSite PhosphoSite-Q16553
TrEMBL Q7Z787
UniProt Splice Variant
Entrez Gene 4061
UniGene
RefSeq
HUGO HGNC:6727
OMIM 601384
CCDS CCDS6394
HPRD 03227
IMGT
EMBL AK311983 BC003392 BC119708 BC119709 CH471162 U42376 U56145 U66711 Z68179
GenPept AAB07513 AAC50519 AAC50616 AAH03392 AAI19709 AAI19710 BAG34922 CAA92321 EAW82287 EAW82288 EAW82290

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca