InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CYB5B

Summary

InnateDB Protein

IDBP-479718.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYB5B

Protein Name

cytochrome b5 type B (outer mitochondrial membrane)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000423679

InnateDB Gene

IDBG-39218 (CYB5B)

Protein Structure

UniProt Annotation

Function

Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. {ECO:0000250}.

Subcellular Localization

Mitochondrion outer membrane {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	6 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0020037	heme binding
GO:0046872	metal ion binding

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005741	mitochondrial outer membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001199 Cytochrome b5-like heme/steroid binding domain
IPR023271 Aquaporin-like

PFAM

PF00173

PRINTS

PR00363

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O43169

PhosphoSite

PhosphoSite-

TrEMBL

Q5HYD9

UniProt Splice Variant

Entrez Gene

80777

UniGene

Hs.706135

RefSeq

HUGO

HGNC:24374

OMIM

611964

CCDS

HPRD

13106

IMGT

EMBL

AB009282 AC026464 AK291576 BC004373 BC014431 BX647922

GenPept

AAH04373 AAH14431 BAA23735 BAF84265 CAI46070