Version 5.4
Homo sapiens Protein: GIMAP7
Summary
InnateDB Protein IDBP-47987.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GIMAP7
Protein Name GTPase, IMAP family member 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000315474
InnateDB Gene IDBG-47985 (GIMAP7)
Protein Structure
UniProt Annotation
Function The dimer has GTPase activity; the active site contains residues from both subunits. {ECO:0000269PubMed:23454188}.
Subcellular Localization Lipid droplet {ECO:0000269PubMed:23454188}. Cytoplasm {ECO:0000269PubMed:23454188}. Note=Colocalizes with GIMAP2 on the surface of cytoplasmic lipid droplets.
Disease Associations
Tissue Specificity Detected in T-cells. {ECO:0000269PubMed:23454188}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006184 GTP catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005811 lipid particle
Protein Structure and Domains
PDB ID
InterPro IPR006703 AIG1
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF04548
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NHV1
PhosphoSite PhosphoSite-Q8NHV1
TrEMBL
UniProt Splice Variant
Entrez Gene 168537
UniGene
RefSeq NP_694968
HUGO HGNC:22404
OMIM
CCDS CCDS5903
HPRD 17039
IMGT
EMBL BC027613
GenPept AAH27613

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca