InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GSTK1

Summary

InnateDB Protein

IDBP-480017.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GSTK1

Protein Name

glutathione S-transferase kappa 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000431049

InnateDB Gene

IDBG-45743 (GSTK1)

Protein Structure

UniProt Annotation

Function

Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).

Subcellular Localization

Peroxisome {ECO:0000269PubMed:14742434}.

Disease Associations

Tissue Specificity

Ubiquitous. {ECO:0000269PubMed:14742434}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	40 [view]
Protein-Protein	39 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0004602	glutathione peroxidase activity
GO:0005102	receptor binding
GO:0015035	protein disulfide oxidoreductase activity

Biological Process

GO:0006749	glutathione metabolic process
GO:0030855	epithelial cell differentiation
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005622	intracellular
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix
GO:0005777	peroxisome
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome