Version 5.4
Homo sapiens Protein: RIPK2
Summary
InnateDB Protein IDBP-480142.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIPK2
Protein Name receptor-interacting serine-threonine kinase 2
Synonyms CARD3; CARDIAK; CCK; GIG30; RICK; RIP2;
Species Homo sapiens
Ensembl Protein ENSP00000429271
InnateDB Gene IDBG-27941 (RIPK2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 86 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 86 [view]
Protein-Protein 84 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0008152 metabolic process
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR011009 Protein kinase-like domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6Q322
UniProt Splice Variant
Entrez Gene 8767
UniGene Hs.103755
RefSeq
HUGO HGNC:10020
OMIM 603455
CCDS
HPRD 04585
IMGT
EMBL AF117829 AY562996
GenPept AAS75586

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca