InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FXN

Summary

InnateDB Protein

IDBP-480344.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FXN

Protein Name

frataxin

Synonyms

CyaY; FA; FARR; FRDA; X25;

Species

Homo sapiens

Ensembl Protein

ENSP00000418015

InnateDB Gene

IDBG-69240 (FXN)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	6 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004322	ferroxidase activity
GO:0008199	ferric iron binding

Biological Process

GO:0016226	iron-sulfur cluster assembly
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR002908 Frataxin/CyaY
IPR017789 Frataxin

PFAM

PF01491

PRINTS

PR00904

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

C9JAX1

UniProt Splice Variant

Entrez Gene

2395

UniGene

RefSeq

HUGO

HGNC:3951

OMIM

606829

CCDS

HPRD

06013

IMGT

EMBL

AL162730

GenPept