Version 5.4
Homo sapiens Protein: SLC45A1
Summary
InnateDB Protein IDBP-481328.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC45A1
Protein Name solute carrier family 45, member 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000418096
InnateDB Gene IDBG-88349 (SLC45A1)
Protein Structure
UniProt Annotation
Function Mediates glucose uptake along the pH gradient. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in adult heart, brain, muscle and kidney, with very strong expression in brain. Also expressed in fetal brain, kidney and lung.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015293 symporter activity
Biological Process
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
PFAM PF07690
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y2W3
PhosphoSite PhosphoSite-Q9Y2W3
TrEMBL X6R9Q4
UniProt Splice Variant
Entrez Gene 50651
UniGene Hs.463036
RefSeq
HUGO HGNC:17939
OMIM 605763
CCDS
HPRD
IMGT
EMBL AF118274 AL356072 CH471130
GenPept AAD27583 CAH70515 EAW71597

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca