Version 5.4
Homo sapiens Protein: VWA1
Summary
InnateDB Protein IDBP-481730.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VWA1
Protein Name von Willebrand factor A domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000417185
InnateDB Gene IDBG-85376 (VWA1)
Protein Structure
UniProt Annotation
Function Promotes matrix assembly. {ECO:0000250}.
Subcellular Localization Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0030198 extracellular matrix organization
GO:0048266 behavioral response to pain
Cellular Component
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005614 interstitial matrix
GO:0005615 extracellular space
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002035 von Willebrand factor, type A
IPR003961 Fibronectin, type III
PFAM PF00092
PF00041
PF01108
PRINTS
PIRSF
SMART SM00327
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PCB0
PhosphoSite PhosphoSite-Q6PCB0
TrEMBL J3QLP3
UniProt Splice Variant
Entrez Gene 64856
UniGene Hs.449009
RefSeq NP_073745
HUGO HGNC:30910
OMIM 611901
CCDS CCDS27
HPRD 18292
IMGT
EMBL AK025868 AK096773 AK291557 AL391244 BC003543 BC059409 CH471183
GenPept AAH03543 AAH59409 BAB15264 BAF84246 BAG53363 CAI22657 EAW56197 EAW56198 EAW56199 EAW56200 EAW56201

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca