Version 5.4
Homo sapiens Protein: PRKCZ
Summary
InnateDB Protein IDBP-481812.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRKCZ
Protein Name protein kinase C, zeta
Synonyms PKC-ZETA; PKC2;
Species Homo sapiens
Ensembl Protein ENSP00000424945
InnateDB Gene IDBG-86108 (PRKCZ)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 171 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 171 [view]
Protein-Protein 170 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000270 Phox/Bem1p
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR020454 Diacylglycerol/phorbol-ester binding
PFAM PF00564
PF00130
PRINTS PR00008
PIRSF
SMART SM00666
SM00109
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F2Z3C5
UniProt Splice Variant
Entrez Gene 5590
UniGene Hs.496255
RefSeq
HUGO HGNC:9412
OMIM 176982
CCDS
HPRD 01504
IMGT
EMBL AL162271 AL391845 AL590822 AL645703
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca