Version 5.4
Homo sapiens Protein: IQGAP2
Summary
InnateDB Protein IDBP-482494.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IQGAP2
Protein Name IQ motif containing GTPase activating protein 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000425941
InnateDB Gene IDBG-29509 (IQGAP2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR001936 Ras GTPase-activating protein
IPR008936 Rho GTPase activation protein
PFAM PF00616
PRINTS
PIRSF
SMART SM00323
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YA28
UniProt Splice Variant
Entrez Gene 10788
UniGene Hs.291030
RefSeq
HUGO HGNC:6111
OMIM 605401
CCDS
HPRD 09253
IMGT
EMBL AC025188 AC026706 AC026725 AC093251 AC112173
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca