Version 5.4
Homo sapiens Protein: CDC25B
Summary
InnateDB Protein IDBP-48369.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDC25B
Protein Name cell division cycle 25 homolog B (S. pombe)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000368918
InnateDB Gene IDBG-48355 (CDC25B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 55 [view]
Protein-Protein 50 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
Biological Process
GO:0000087 mitotic M phase
GO:0006470 protein dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000751 M-phase inducer phosphatase
IPR001763 Rhodanese-like domain
PFAM PF06617
PF00581
PRINTS PR00716
PIRSF
SMART SM00450
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G8JLH2
UniProt Splice Variant
Entrez Gene 994
UniGene Hs.153752
RefSeq NP_001274447
HUGO HGNC:1726
OMIM 116949
CCDS CCDS74701
HPRD 00307
IMGT
EMBL AL109804 CH471133
GenPept EAX10489 EAX10495

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca