InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PFDN1

Summary

InnateDB Protein

IDBP-48424.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PFDN1

Protein Name

prefoldin subunit 1

Synonyms

PDF; PFD1;

Species

Homo sapiens

Ensembl Protein

ENSP00000261813

InnateDB Gene

IDBG-48422 (PFDN1)

Protein Structure

UniProt Annotation

Function

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 116 experimentally validated interaction(s) in this database.

Experimentally validated
Total	116 [view]
Protein-Protein	116 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0051082	unfolded protein binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006457	protein folding
GO:0007049	cell cycle
GO:0021537	telencephalon development
GO:0021549	cerebellum development
GO:0030036	actin cytoskeleton organization
GO:0042113	B cell activation
GO:0044267	cellular protein metabolic process
GO:0051084	'de novo' posttranslational protein folding