InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IP6K1

Summary

InnateDB Protein

IDBP-484439.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IP6K1

Protein Name

inositol hexakisphosphate kinase 1

Synonyms

IHPK1; PiUS;

Species

Homo sapiens

Ensembl Protein

ENSP00000420762

InnateDB Gene

IDBG-35427 (IP6K1)

Protein Structure

UniProt Annotation

Function

Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:11502751}. Nucleus {ECO:0000269PubMed:11502751}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000832	inositol hexakisphosphate 5-kinase activity
GO:0005524	ATP binding
GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity
GO:0052723	inositol hexakisphosphate 1-kinase activity
GO:0052724	inositol hexakisphosphate 3-kinase activity

Biological Process

GO:0043647	inositol phosphate metabolic process
GO:0044281	small molecule metabolic process
GO:0045087	innate immune response (InnateDB)
GO:0046854	phosphatidylinositol phosphorylation