Version 5.4
Homo sapiens Protein: TLR10
Summary
InnateDB Protein IDBP-484777.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TLR10
Protein Name toll-like receptor 10
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000427606
InnateDB Gene IDBG-13548 (TLR10)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
Biological Process
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0034166 toll-like receptor 10 signaling pathway
GO:0045087 innate immune response (InnateDB)
GO:0050707 regulation of cytokine secretion
GO:0050729 positive regulation of inflammatory response
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RHW6
UniProt Splice Variant
Entrez Gene 81793
UniGene Hs.730896
RefSeq
HUGO HGNC:15634
OMIM 606270
CCDS
HPRD 05884
IMGT
EMBL AC108044 AC118137
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca