InnateDB Protein
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IDBP-49094.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CSRP2
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Protein Name
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cysteine and glycine-rich protein 2
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Synonyms
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CRP2; LMO5; SmLIM;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000310901
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InnateDB Gene
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IDBG-49092 (CSRP2)
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Protein Structure
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Function |
Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in the aorta, but not in heart and skeletal muscle.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
8
[view]
|
Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
1
[view]
|
RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001781
Zinc finger, LIM-type
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PFAM |
PF00412
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PRINTS |
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PIRSF |
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SMART |
SM00132
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TIGRFAMs |
|
Modification |
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SwissProt |
Q16527
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PhosphoSite |
PhosphoSite-Q16527
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TrEMBL |
A0A024RBB5
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UniProt Splice Variant |
|
Entrez Gene |
1466
|
UniGene |
Hs.603478
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RefSeq |
NP_001312
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HUGO |
HGNC:2470
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OMIM |
601871
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CCDS |
CCDS9015
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HPRD |
03523
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IMGT |
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EMBL |
BC000992
BT019913
CH471054
U46006
U57646
U95018
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GenPept |
AAC27344
AAC51753
AAC51755
AAH00992
AAV38716
EAW97336
EAW97337
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