Version 5.4
Homo sapiens Protein: TMUB1
Summary
InnateDB Protein IDBP-49212.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMUB1
Protein Name transmembrane and ubiquitin-like domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000297533
InnateDB Gene IDBG-49210 (TMUB1)
Protein Structure
UniProt Annotation
Function May contribute to the regulation of translation during cell-cycle progression. May contribute to the regulation of cell proliferation (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269PubMed:19254477}. Nucleus {ECO:0000269PubMed:19254477}. Note=Predominantly nuclear during growth arrest (By similarity). Actively exported from the nucleus in dividing cells. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000626 Ubiquitin-like
IPR029071 Ubiquitin-related domain
PFAM PF00240
PF14560
PRINTS
PIRSF
SMART SM00213
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BVT8
PhosphoSite PhosphoSite-Q9BVT8
TrEMBL C9JE12
UniProt Splice Variant
Entrez Gene 83590
UniGene Hs.726215
RefSeq NP_001129516
HUGO HGNC:21709
OMIM 614792
CCDS CCDS5920
HPRD 12910
IMGT
EMBL AC010973 AK314035 AY037155 AY358481 AY603380 BC000936 BC033182 CH471173
GenPept AAH00936 AAH33182 AAK67645 AAQ88845 AAU00156 BAG36745 EAW54030 EAW54032

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca