InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: WDR55

Summary

InnateDB Protein

IDBP-49301.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

WDR55

Protein Name

WD repeat domain 55

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000351100

InnateDB Gene

IDBG-49299 (WDR55)

Protein Structure

UniProt Annotation

Function

Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000250}. Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0006364	rRNA processing
GO:0008150	biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005730	nucleolus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001680 WD40 repeat
IPR017422 WD repeat protein 55
IPR017986 WD40-repeat-containing domain

PFAM

PF00400

PRINTS

PIRSF

PIRSF038169

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9H6Y2

PhosphoSite

PhosphoSite-Q9H6Y2

TrEMBL

G3V1J0

UniProt Splice Variant

Entrez Gene

54853

UniGene

Hs.608636

RefSeq

NP_060176

HUGO

HGNC:25971

OMIM

CCDS

CCDS4235

HPRD

08614

IMGT

EMBL

AC116353 AK000202 AK025355 BC068485 CH471062

GenPept

AAH68485 BAA91006 BAB15118 EAW62025