Version 5.4
Homo sapiens Protein: PDHA1
Summary
InnateDB Protein IDBP-49610.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDHA1
Protein Name pyruvate dehydrogenase (lipoamide) alpha 1
Synonyms PDHA; PDHCE1A; PHE1A;
Species Homo sapiens
Ensembl Protein ENSP00000369132
InnateDB Gene IDBG-49600 (PDHA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
Experimentally validated
Total 36 [view]
Protein-Protein 36 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001017 Dehydrogenase, E1 component
IPR029061 Thiamin diphosphate-binding fold
PFAM PF00676
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9UNV7
UniProt Splice Variant
Entrez Gene 5160
UniGene Hs.530331
RefSeq
HUGO HGNC:8806
OMIM 300502
CCDS
HPRD 02420
IMGT
EMBL AF085457 AL732326 U75933 U75934 U75935 U75936
GenPept AAB39723 AAB39724 AAB39725 AAB39726 AAD16047

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca