InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CD200

Summary

InnateDB Protein

IDBP-49805.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD200

Protein Name

CD200 molecule

Synonyms

MOX1; MOX2; MRC; OX-2;

Species

Homo sapiens

Ensembl Protein

ENSP00000312766

InnateDB Gene

IDBG-49799 (CD200)

Protein Structure

UniProt Annotation

Function

Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.

Subcellular Localization

Cell membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	2 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0045087	innate immune response (InnateDB)
GO:0050776	regulation of immune response

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003596 Immunoglobulin V-set, subgroup
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF07686
PF00047

PRINTS

PIRSF

SMART

SM00406
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P41217