InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PWP2

Summary

InnateDB Protein

IDBP-5018.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PWP2

Protein Name

PWP2 periodic tryptophan protein homolog (yeast)

Synonyms

EHOC-17; PWP2H; UTP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000291576

InnateDB Gene

IDBG-402099 (PWP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Nucleus, nucleolus {ECO:0000269PubMed:12429849}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004252	serine-type endopeptidase activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006508	proteolysis
GO:0007165	signal transduction

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001680 WD40 repeat
IPR007148 Small-subunit processome, Utp12
IPR011047 Quinonprotein alcohol dehydrogenase-like superfamily
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat

PFAM

PF00400
PF04003

PRINTS

PR00320

PIRSF

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt