InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: INSIG1

Summary

InnateDB Protein

IDBP-50277.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

INSIG1

Protein Name

insulin induced gene 1

Synonyms

CL-6; CL6;

Species

Homo sapiens

Ensembl Protein

ENSP00000344035

InnateDB Gene

IDBG-50271 (INSIG1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.

Experimentally validated
Total	27 [view]
Protein-Protein	26 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0008152	metabolic process
GO:0008283	cell proliferation
GO:0032933	SREBP signaling pathway
GO:0044281	small molecule metabolic process
GO:1901303	negative regulation of cargo loading into COPII-coated vesicle

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0032937	SREBP-SCAP-Insig complex

Protein Structure and Domains

PDB ID

InterPro

IPR025929 Insulin-induced protein family

PFAM

PF07281

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O15503

PhosphoSite

PhosphoSite-O15503

TrEMBL

C9JSG8

UniProt Splice Variant

Entrez Gene

3638

UniGene

Hs.520819

RefSeq

NP_938151

HUGO

HGNC:6083

OMIM

602055

CCDS

CCDS5939

HPRD

03633

IMGT

EMBL

AC144652 AC231970 AK291675 AY112745 BC001880 BT007227 CH236962 CH471149 DN996424 U96876

GenPept

AAB69121 AAH01880 AAM44086 AAP35891 BAF84364 EAL23729 EAL23730 EAX04529 EAX04530