InnateDB Protein
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IDBP-50660.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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EIF1AX
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Protein Name
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eukaryotic translation initiation factor 1A, X-linked
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Synonyms
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eIF-1A; eIF-4C; EIF1A; EIF1AP1; EIF4C;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000368927
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InnateDB Gene
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IDBG-50658 (EIF1AX)
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Protein Structure
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Function |
Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
17
[view]
|
Protein-Protein |
16
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001253
Translation initiation factor 1A (eIF-1A)
IPR006196
RNA-binding domain, S1, IF1 type
IPR012340
Nucleic acid-binding, OB-fold
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PFAM |
PF01176
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PRINTS |
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PIRSF |
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SMART |
SM00652
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TIGRFAMs |
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Modification |
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SwissProt |
P47813
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PhosphoSite |
PhosphoSite-P47813
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
1964
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UniGene |
Hs.737196
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RefSeq |
NP_001403
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HUGO |
HGNC:3250
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OMIM |
300186
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CCDS |
CCDS14196
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HPRD |
02174
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IMGT |
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EMBL |
AK312320
AL732366
BC000793
BC067851
BT007064
L18960
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GenPept |
AAA19812
AAH00793
AAH67851
AAP35727
BAG35242
CAI40550
CAI40551
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