Version 5.4
Homo sapiens Protein: AMDHD1
Summary
InnateDB Protein IDBP-51866.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AMDHD1
Protein Name amidohydrolase domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000266736
InnateDB Gene IDBG-51864 (AMDHD1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO:0046872 metal ion binding
GO:0050480 imidazolonepropionase activity
Biological Process
GO:0006548 histidine catabolic process
GO:0019556 histidine catabolic process to glutamate and formamide
GO:0019557 histidine catabolic process to glutamate and formate
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR005920 Imidazolonepropionase
IPR006680 Amidohydrolase 1
IPR011059 Metal-dependent hydrolase, composite domain
IPR013108 Amidohydrolase 3
PFAM PF01979
PF07969
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96NU7
PhosphoSite PhosphoSite-Q96NU7
TrEMBL
UniProt Splice Variant
Entrez Gene 144193
UniGene Hs.424907
RefSeq NP_689648
HUGO HGNC:28577
OMIM
CCDS CCDS9057
HPRD 14605
IMGT
EMBL AB075878 AC126174 AK054617 AK290828 BC029146 CH471054
GenPept AAH29146 BAB70775 BAD38660 BAF83517 EAW97552

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca