Homo sapiens Protein: KLHL15
Summary
InnateDB Protein IDBP-52658.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLHL15
Protein Name kelch-like 15 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000332791
InnateDB Gene IDBG-52656 (KLHL15)
Protein Structure
UniProt Annotation
Function Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000269PubMed:14528312}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR006652 Kelch repeat type 1
IPR011333 BTB/POZ fold
IPR011705 BTB/Kelch-associated
IPR013069 BTB/POZ
IPR017096 Kelch-like protein, gigaxonin type
PFAM PF01344
PF07707
PF00651
PRINTS
PIRSF PIRSF037037
SMART SM00225
SM00612
SM00875
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96M94
PhosphoSite PhosphoSite-Q96M94
TrEMBL V9HWF1
UniProt Splice Variant
Entrez Gene 80311
UniGene Hs.495854
RefSeq NP_085127
HUGO HGNC:29347
OMIM
CCDS CCDS35217
HPRD
IMGT
EMBL AB051464 AK057298 AL834313 BC015415 BC109058 BC109059 CH471074 EU794630
GenPept AAH15415 AAI09059 AAI09060 ACJ13684 BAB21768 BAB71415 CAD38983 EAW99008