InnateDB Protein
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IDBP-532138.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Mitd1
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Protein Name
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MIT, microtubule interacting and transport, domain containing 1
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Synonyms
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1500032H18Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000123009
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InnateDB Gene
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IDBG-146409 (Mitd1)
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Protein Structure
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Function |
Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex. {ECO:0000250}.
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Subcellular Localization |
Late endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Midbody {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=During cytokinesis, recruited to the midbody via interaction with CHMP1A. Interacts with membranes enriched in phosphoinositides (By similarity). {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1916278
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InterPro |
IPR007330
MIT
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PFAM |
PF04212
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PRINTS |
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PIRSF |
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SMART |
SM00745
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TIGRFAMs |
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Modification |
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SwissProt |
Q8VDV8
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PhosphoSite |
PhosphoSite-Q8VDV8
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
69028
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UniGene |
Mm.63984
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RefSeq |
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MGI ID |
1WFD
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MGI Symbol |
Mitd1
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OMIM |
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CCDS |
CCDS35542
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HPRD |
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IMGT |
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EMBL |
AK005342
AK171903
BC020137
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GenPept |
AAH20137
BAB23964
BAE42727
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